Cell Biochemistry Martinsried


Selected Literature References:
Predictive Medicine by Cytomics,
Medical and Clinical Bioinformatics

G.Valet

  • < Cell Biochemistry

    1. Medical Cytomics, Clinical Cytomics:

    1.1 Predictive Medicine by Cytomics, Human Cytome Project
    13. AOH Gerstner, G Valet Cytomics and Predictive Medicine for Oncology. In: ed WCS Cho, An Omics Perspective on Cancer Research, Springer Heidelberg (2010), p 183-199.
    12. A Tarnok, A Pierzchalski, G Valet. Potential of a cytomics top-down strategy for drug discovery. Curr Med Chem 11: 1719-1729 (2010).
    11. G Valet, RF Murphy, JP Robinson, A Tarnok, A Kriete. Cytomics - from cell states to predictive medicine. In: Computational Systems Biology. Eds: A Kriete, R Eils, Elsevier, Amsterdam (2006), p 363-381.
    10. G Valet. Cytomics, human cytome project and systems biology: top-down resolution of the molecular biocomplexity of organisms by single cell analysis. Cell Proliferation 38:171-174(2005).
    9. G Valet. Human cytome project, cytomics and systems biology: the incentive for new horizons in cytometry. Cytometry Part A 64A:1-2 (2005).
    8. G Valet. Cytomics: an entry to biomedical cell systems biology. Cytometry Part A 63A:67-68 (2005).
    7. G Valet. Diagnostic versus predictive flow cytometry. Lab Hematol 10:166-168 (2004).
    6. G Valet, A Tarnok. Potential and challenges of a human cytome project. JBRHA 18: 87-91 (2004).
    5. G Valet. Predictive medicine by cytomics and the challenges of a human cytome project. In: Business Briefing: Future Drug Discovery 2004, Ed: E Cooper, World Markets Research Center Ltd, London (2004) p 46-51.
    4. G Valet, A Tárnok. Cytomics in predictive medicine. In: Business Briefing: Future Drug Discovery (2004), Ed: E Cooper, World Markets Research Center Ltd, London 2004, p 1-3
    3. G Valet, A Tárnok. Cytomics and Predictive Medicine. Cytometry 53B:1-3 (2003).
    2. A Tárnok, GK Valet Cytomics in predictive medicine. In: Advanced Biomedical and Clinical Diagnostic Systems II. Eds: GE Cohn, WS Grundfest, DA Benaron, T Vo-Dinh, Proceedings SPIE, Bellingham, WA (2004), Vol 5318, p 12-22

    1. G Valet. Predictive Medicine by Cytomics: Potential and Challenges. J.Biol.Regulators 16:164-167 (2002).

    1.2 Leukocytes, Thrombocytes, Sepsis, Immunology
    12. AM Jacobi, M Odendahl, K Reiter, A Bruns, GM Burmester, A Radbruch, G Valet, PE Lipsky, Th Dörner. Correlation between circulating CD27high plasma cells and disease activity in patients with systemic lupus erythematosus. Arthritis & Rheumatism 48:1332-1342 (2003).
    11. J Bocsi, J Hambsch, P Osmancik, P Schneider, G Valet, A Tárnok. Preoperative prediction of pediatric patients with effusions and edema following cardiopulmonary bypass surgery by serological and routine laboratory data. Critical Care 6:226-233 (2002).
    10. A Tárnok, J Bocsi, M Pipek, P Osmancik, G Valet. Preoperative prediction of postoperative edema and effusion in pediatric cardiac surgery by altered antigen expression patterns on granulocytes and monocytes. Cytometry (CCC) 46:247-253 (2001).
    9. A Tárnok, M Pipek, G Valet, J Richter, J Hambsch, P Schneider. Children with post-capillary leak syndrome can be distinguished by antigen expression on neutrophil and monocytes. in: System and Technologies for Clinical Diagnostics and Drug Discovery II, eds: G.E.Cohn, J.C.Owicki, A.Katzir. SPIE Vol.3603:61-71, (1999).
    8. H Gabriel, A Urhausen, G Valet, U Heidelbach, W Kindermann. Overtraining and immune system: A prospective longitudinal study in endurance athletes. Med.Sci.Sports Exerc. 30: 1151-1157 (1998).
    7. GK Valet, G Roth, W Kellermann. Risk assessment for intensive care patients by automated classification of flow cytometric data. In: Phagocyte Function, Eds. JP Robinson, GF Babcock, Wiley-Liss Inc, New York (1998), p 289-306.
    6. A Tárnok, J Hambsch, M Borte, G Valet, P Schneider. Immunological and serological discrimination of children with and without post-surgical capillary leak syndrome. in: The Immune Consequences of Trauma, Shock and Sepsis Vol.III, Ed: E.Faist, Monduzzi Editore, Bologna (1997), p.845-849.
    5. G Valet, M Valet, D Tschöpe, H Gabriel, G Rothe, W Kellermann, H Kahle. White cell and thrombocyte disorders: Standardized, self-learning flow cytometric list mode data classification with the CLASSIF1 program system. Ann NY Acad Sci 677: 233-251 (1993).
    4. G Rothe, W Kellermann, J Briegel, B Schaerer, G Valet. Activation of neutrophils by tumor necrosis factor-a during sepsis. in: Immune Consequences of Trauma, Shock and Sepsis Vol.II, Ed: E. Faist, J.Ninnemann, D.Green, Springer Verlag, Berlin (1993), p.727-733.
    3. RP Linke, V Bock, G Valet, G Rothe. The oxidative burst reaction of neutrophils is reduced by the acute phase serum amyloid-A protein. In: Immune Consequences of Trauma, Shock and Sepsis Vol.II, Eds: E Faist, J Ninnemann, D Green, Springer Verlag, Berlin (1993), p 419-422.
    2. G Rothe, W Kellermann, G Valet. Flow cytometric parameters of neutrophil function as early indicators of sepsis- or trauma-related pulmonary or cardiovascular organ failure. J.Lab.Clin.Invest. 115:52-61 (1990).
    1. G Rothe, W Kellermann, G Valet. Flow cytometric analysis of phagocytosis, respiratory burst, intracellular pH and cytosolic free calcium of granulocytes of posttraumatic and septic patients. in: Immune Consequences of Trauma, Shock and Sepsis, eds: E Faist, J Ninnemann, D Green, Springer Verlag, Berlin (1989), p.235- 240.

    1.3 Malignancies
    15. G Valet, HG Hoeffkes. Data pattern analysis for the individualized pretherapeutic identification of high risk diffuse large B-cell lymphoma (DLBCL) patients by cytomics. Cytometry Part A 59A:232-236 (2004)
    14. G Valet, R Repp, H Link, G Ehninger, M Gramatzki and SHG-AML study group. Pretherapeutic identification of high risk acute myeloid leukemia (AML) patients from immunophenotype, cytogenetic and clinical parameters. Cytometry 53B:4-10 (2003).
    13. G Valet, M Arland, A Franke, Ch Kahl, HG Höffkes. Discrimination of chronic lymphocytic leukemia of B-cell type by computerized 3-color flow cytometric immunophenotypes of bone marrow aspirates and peripheral blood. Lab.Hematology14:134-142 (2002).
    12. G Valet, H Kahle, F Otto, E Bräutigam, L Kestens. Prediction and precise diagnosis of diseases by data pattern analysis in multiparameter flow cytometry: Melanoma, juvenile asthma and human immunodeficiency virus infection. Methods in Cell Biology 64:487-508 (2001).
    11. R Bartsch, M Arland, St Lange, Ch Kahl, G Valet,HG Höffkes. Lymphoma discrimination by computerized triple matrix analysis of list mode data from three-color flow cytometric immunophenotypes of bone marrow aspirates. Cytometry 41:9-18 (2000).
    10. BEM van Driel, GK Valet, H Lyon, U Hansen, JY Song, CJF van Noorden. Prognostic estimation of survival of colorectal cancer patients with the quantitative histochemical assay of G6PDH activity and the multiparameter classification program CLASSIF1. Cytometry(Comm.Clin.Cytometry) 38:176-183 (1999).
    9. G Valet, HG Höffkes. Automated classification of patients with chronic lymphatic leukemia and immunocytoma from flow cytometric three colour immunophenotypes. Cytometry (Comm.Clin.Cytometry) 30: 275-288 (1997).
    8. HG Höffkes HG, G Schmidtke, U Schmücker, G Brittinger, G Valet. Computerized analysis of cells from patients with acute myelogeneous leukemia prepared by density gradient centrifugation or erythrocyte lysis and measured by flow cytometry. Lab.Hematol.1:128-134 (1995).
    7. F Liewald, R Hatz, M Storck, KH Orend, M Weiss, G Wulf, G Valet, L Sunder-Plasmann. Prognostic value of deoxyribonucleic acid aneuploidy in primary non small-cell lung carcinomas and their metastases. J.Thoracic Cardiovasc.Surgery 105:1476-1482 (1992).
    6. F Liewald L Sunder-Plassmann, H Dienemann, H Kahle, G Wulf, G Valet. Prognostic value of flow cytometrically determined DNA-ploidy, intracellular pH and esterase activity of non-small cell lung carcinoma. Anal.Cell.Pathology 4:103-114 (1992).
    5. F Liewald, N Demmel, R Wirsching, H Kahle, G Valet. Intracellular pH, esterase activity and DNA measurements of human lung carcinomas by flow-cytometry. Cytometry 11: 341-348 (1990).
    4. G Valet, HH Warnecke, H Kahle. Automated diagnosis of malignant and other abnormal cells by flow-cytometry using the newly developed DIAGNOS1 program system. In: Proc Int Symp Histometry 1986, Eds: G Burger, B Ploem, K Goerttler, Academic Press, London (1987), p 58-67.
    3. G Valet, L Rüssmann, R Wirsching. Automated flow-cytometric identification of colo-rectal tumor cells by simultaneouus DNA, CEA-antibody and cell volume measurements. J.Clin.Chem.Clin.Biochem. 22:935-942 (1984).
    2. G Valet, MG Ormerod, HH Warnecke, G Benker, G.Ruhenstroth-Bauer. Sensitive three-parameter flow-cytometric detection of abnormal cells in human cervical cancers: A pilot study. J.Canc.Res.Clin.Oncol. 102:177-184 (1981).
    1. OF Scheiffarth, G Valet, R Dvorak, S Baur, V Kachel, J Zander, G Ruhenstroth-Bauer. Flow cytometric characterisation of tumor associated changes in gynecologic malignancies. In: Separation of Cells and Subcellular Elements, Ed: H Peeters, Pergamon Press, Oxford (1979), p 11-16.

    1.4 Neurology
    2. RB Banati, P Schubert, G Rothe, J Gehrmann, K Rudolphi, G Valet, GW Kreutzberg. Modulation of intracellular formation of reactive oxygen intermediates in peritoneal macrophages and microglia/brain macrophages by propentofylline. J Cerebral Blood Flow and Metabolism 14: 145-149 (1994).
    1. RB Banati, G Rothe, G Valet, GW Kreutzberg. Detection of lysosomal cysteine proteinases in microglia: Flow cytometric measurement and histochemical localization of cathepsin B and L. Glia 7: 183-191 (1993).

    2. Medical Bioinformatics (Data Pattern Classification):

    16. M Valet, G Valet, T Sprenger, C Sorg, H Gündel, TR Tölle. Self-learning classification of fMRI data with the CLASSIF1 software - an example with somatoform pain disorder. In: Proc 3rd Int Congr Neuropathic Pain NeuPSIG, ed: CD Wells, Monduzzi Editore, Bologna (2010), p 235-238.
    15. G Valet. Prädiktivmedizin mittels Zytomik: Möglichkeiten der Datenmusteranalyse. In: Angewandte Durchflusszytometrie. Eds: U Sack, A Tarnok, G Rothe. Karger Verlag, Basel (2007) p.237-250.
    14. G Valet, C Esser. Data sieving analysis as a novel method to assess immunotoxic exposure to dioxins retrospectively. Int Immunopharmacol 6:1364-1375(2006).
    13. G Valet. Human cytome project: A new potential for drug discovery. In: Las Omicas genomica, proteomica, citomica y metabolomica: modernas tecnologias para desarrollo de farmacos. Ed: Real Academia Nacional de Farmacia, Madrid (2005) p 207-228.
    12. G Valet, G, H Kahle, F Otto, E Bräutigam, L Kestens Prediction and precise diagnosis of diseases by data pattern analysis in multiparameter flow cytometry: Melanoma, Juvenile Asthma, HIV-infection. in: Cytometry (3rd edition), eds: Z Darzynkiewicz, JP Robinson, H.A.Crissman, Academic Press, San Diego. Methods in Cell Biology 64:487-508 (2001).
    11. G Valet, G Roth, W Kellermann. Risk assessment for intensive care patients by automated classification of flow cytometric oxidative burst, serine and cysteine proteinase activity measurements using CLASSIF1 triple matrix analysis. In: Cytometric Cellular Analysis, Eds: J.P.Robinson, G.Babcock, Wiley-Liss, New York (1998), p.289-306
    10. G Valet, HG Höffkes. Automated classification of patients with chronic lymphatic leukemia and immunocytoma from flow cytometric three colour immunophenotypes. Cytometry (CCC) 30:275-288 (1997).
    9. G Valet, M Valet, D Tschöpe, H Gabriel, G Rothe, W Kellermann, H Kahle. White cell and thrombocyte disorders: Standardized, self-learning flow cytometric list mode data classification with the CLASSIF1 program system. Ann.NY Acad.Sci.677:233-251 (1993).
    8. G Valet, HH Warnecke, H Kahle. Automated diagnosis of malignant and other abnormal cells by flow-cytometry using the DIAGNOS1 program system. In: Clinical Cytometry and Histometry, Eds: G.Burger, J.Ploem, K.Goerttler, Academic press, London (1987), p.58-65
    7. G Valet. Graphical respresentation of three parameter flow cytometer histograms by a newly developed FORTRAN IV computer program. In: Flow Cytometry IV, Eds: OD Laerum T Lindmo, E Thorud, Universitetsforlaget, Oslo (1980), p 125-129.
    6. G Valet, G Hanser, G Ruhenstroth-Bauer. Computer analysis of two parameter (volume/DNA) histograms of rat bone marrow cells measured by flow cytometry. 3rd Int.Symp.on Pulse Cytophotometry, Wien 1977, In: Pulse-Cytophotometry III, Eds: D Lutz, European Press Medikon, Ghent (1978), p 127-136.
    5. G Valet, H Hofmann, G Ruhenstroth-Bauer. The computer analysis of volume distribution curves: Demonstration of two erythrocyte populations of different size in the young guinea pig, and analysis of the mechanism of immune lysis of cells by antibody and complement. J Histochem Cytochem 24: 231-246 (1976).
    4. G Valet, S Silz, H Metzger, G Ruhenstroth-Bauer. Electrical sizing of liver cell nuclei by the particle beam method. Mean volume, volume distribution and electrical resistance. Acta Hepato-Gastroenterol 22: 274-281 (1975).
    3. G Valet, W Opferkuch. Mechanism of complement induced cell lysis. Demonstration of a three step mechanism of EAC1-8 cell lysis by C9, and of a non osmotic swelling of erythrocytes. J Immunol 115: 1028-1033 (1975).
    2. G Ruhenstroth-Bauer, G Valet, V Kachel, N Boss. Die elektrische Volumenmessung von Blutzellen bei der Erythropoese, bei Rauchern, Herzinfarkt- und Leukämiepatienten, sowie von Leberzellkernen. Naturwiss 61: 260-266 (1974).
    1. G Valet, H Metzger, V Kachel, G Ruhenstroth-Bauer. Der Nachweis verschiedener Erythrozytenpopulationen bei der Ratte. Blut 24: 42-53 (1972).

    3. Concepts & General Flow Cytometry:

    6. G Valet, E Endl, S Müller. 20 years of the German Society for Cytometry: Past and future concepts. Cytometry Part A 79A:891-893 (2011).
    5. G Valet. Concept development in flow cytometry. In: eds U Sack, A Tarnok, G Rothe, Cellular diagnostics, Karger Basel (2009), p 29-52.
    4. G Valet. Concepts and history of flow cytometry and cytomics at Max-Planck-Institut für Biochemie, Martinsried (1960-2006). In: ed J P Robinson, 60 Years Innovation in Cytometry, Purdue Cytometry CD Vol.7, ISBN 978-1-890473-10-5, (2007).
    3. G Valet. Die Durchflusszytometrie im Wandel der Forschungskonzepte. In: Angewandte Durchflusszytometrie. Eds: U Sack, A Tarnok, G Rothe. Karger Verlag, Basel (2007) p.1-26.
    2. G Valet. Past and present concepts in flow cytometry: A European perspective. J.Biol.Regulators 17:213-222 (2003).
    1. A Raffael, C Th Nebe, G Valet. Grundlagen der Durchflußzytometrie. In: Durchflußzytometrie in der klinischen Zelldiagnostik, Eds: G Schmitz, G Rothe, Schattauer Verlag, Stuttgart (1994), p.3-49.

    4.Flow Cytometric Methods:


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    Internet: https://www.classimed.de
    last update: May 03,2020
    first display: Sep 10,2002